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Monoclonal Antibody Treatment: What you need to know

What are Monoclonal Antibodies?

Monoclonal antibodies (MAB) are laboratory made proteins that mimic the immune system's ability to fight off harmful antigens such as the COVID-19 virus. These proteins are designed to help provide passive immunity by giving the body man-made antibodies to protect itself. While MAB provides the body with passive immunity, the COVID-19 vaccine will provide active immunity that helps the body make its own antibodies to protect itself. (FDA, 2021)

How do Monoclonal Antibodies help treat COVID-19?

When the immune system meets a foreign substance in the body, it forms antibodies to help attack that foreign substance. The next time this substance appears in the immune system, the body is now able to produce the same antibodies to help fight off the substance before it makes a person sick. These types of naturally occurring antibodies provide active immunity against viruses such a COVID-19. 

MAB treatments are man-made antibodies that are administered directly through an infusion or injection. This allows the body to begin fighting off viruses such a COVID-19 before it has the ability to produce these antibodies and fight the virus on its own.

Are you eligible to receive MAB?

There are certain medical conditions associated with individuals who are considered high risk for severe COVID-19 and those who are more likely to become severely ill as a result. Severe illness means that a person with COVID-19 may need hospitalization, intensive care or a ventilator to assist their natural breathing.

Individuals that are considered high risk and are eligible for MAB may belong to some of the following groups:

  • Elderly (65 years of age or older)
  • Obese or overweight
  • Pregnant
  • Chronic kidney disease
  • Diabetes
  • Immunosuppressive disease or immunosuppressive treatment
  • Cardiovascular disease or hypertension
  • Chronic lung disease
  • Sickle cell disease
  • Neurodevelopmental disorders

Where to receive Monoclonal Antibody Treatment

The Parrish Medical Center Infusion Center opened its MAB treatment clinic beginning on February 2, 2021 and has provided more than 130 treatments to-date. MAB is provided in an outpatient setting and is available by appointment only to those who meet the FDA EUA criteria. For more information, screening and appointment scheduling, please call the Infusion Center at (321) 268-6730 or visit